McLornan, Donal P;
Psaila, Bethan;
Ewing, Joanne;
Innes, Andrew;
Arami, Siamak;
Brady, Jessica;
Butt, Nauman M;
Cargo, Catherine;
Cross, Nicholas C. P;
Francis, Sebastian;
Frewin, Rebecca;
Garg, Mamta;
Godfrey, Anna L;
Green, Anna;
Khan, Alesia;
Knapper, Steve;
Lambert, Jonathan;
McGregor, Andrew;
McMullin, Mary Frances;
Nangalia, Jyoti;
Neelakantan, Pratap;
Woodley, Claire;
Mead, Adam;
Somervaille, Tim C. P;
Harrison, Claire N.
This document represents an update of the British Society for Haematology guideline on Myelofibrosis first published in 2012 and updated in 2015 These guidelines aim to pro-vide healthcare professionals with clear guidance on stratified management for primary myelofibrosis (PMF)...
Scully, M;
Rayment, R;
Clark, A;
Westwood, J. P;
Cranfield, T;
Gooding, R;
Bagot, C. N;
Taylor, A;
Sankar, V;
Gale, D;
Dutt, T;
McIntyre, J;
Lester, W.
The objective of this guideline is to provide healthcare professionals with clear, up-to-date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement-mediated haemolytic uraemic syndrome (CM HUS); these ar...
This guideline covers assessment and early management of head injury in babies, children, young people and adults. It aims to ensure that people have the right care for the severity of their head injury, including direct referral to specialist care if needed....
Six digitally enabled therapies can be used as treatment options for
adults with anxiety disorders while further evidence is generated on their
clinical and cost effectiveness, once they have appropriate approval.
The following technologies can only be used once they have Digital
Technology Assessment Cr...
Three digitally enabled therapies can be used as treatment options for
adults with depression while further evidence is generated on their
clinical and cost effectiveness. The therapies should be used with
support from a trained practitioner or therapist in NHS Talking Therapies
for anxiety and depressio...
Evidence-based recommendations on percutaneous transluminal renal sympathetic denervation for resistant hypertension. This involves inserting a device through the skin (percutaneous) into an artery in the thigh and then into the renal arteries (transluminal). It sends radio or sound waves to destroy the ...
NICE is unable to make a recommendation on teclistamab (Tecvayli) for treating relapsed or refractory multiple myeloma after 3 or more therapies in adults. This is because Agios did not provide an evidence submission. We will review this decision if the company decides to make a submission....
Evidence-based recommendations on nivolumab (Opdivo) with fluoropyrimidine- and platinum-based chemotherapy for untreated unresectable advanced, recurrent, or metastatic oesophageal squamous cell carcinoma.
Commercial arrangement
There is a commercial arrangement for nivolumab. NHS organisations can get...
Evidence-based recommendations on Kinesia 360 and KinesiaU (Great Lakes NeuroTechnologies), PDMonitor (PD Neurotechnology), Personal KinetiGraph (Global Kinetics) and STAT‑ON (Sense4care) for remote monitoring of Parkinson’s disease....
Evidence-based recommendations on trastuzumab deruxtecan (Enhertu) for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 treatments in adults.
Commercial arrangement
There is a managed access agreement, which includes a patient access scheme, for trastuzumab derux...
